This study shows that electrical muscle stimulation improves tendon healing and muscle recovery after Achilles tendon rupture, while static stretching has no additional benefit.

Journal of Orthopaedic Research® · Jan 12, 2025Peer-reviewedPhysiology

Effectiveness of Exercise Intervention in Preventing Active Arthritis Exacerbation in an SKG Mouse Model of Rheumatoid Arthritis

Kaichi Ozone, Tatsunori Kumagai, Kohei Arakawa, Takehito Sugasawa, Wenchao Gu, Sora Kawabata, Naoki Shimada, Haruna Takahashi, Moe Yoneno, Yuki Minegishi, Kei Takahata, Michiaki Sato, Yuichiro Oka, Naohiko Kanemura

This study shows that low-intensity exercise reduces arthritis severity and inflammation in SKG mice with rheumatoid arthritis.

bioRxiv · Aug 25, 2024 · PreprintMolecular Biology

Joint Instability Causes Catabolic Enzyme Production in Chondrocytes prior to Synovial Cells in Novel Non-Invasive ACL ruptured Mouse Model

Kei Takahata, Kohei Arakawa, Saaya Enomoto, Yuna Usami, K. Nogi, R. Saitou, Kaichi Ozone, Haruna Takahashi, Moe Yoneno, Takanori Kokubun

This study establishes a non-invasive ACL-ruptured mouse model to investigate OA progression, finding that chondrocytes respond to mechanical stress before synovial cells.

Osteoarthritis and Cartilage · Dec 14, 2022Peer-reviewedMolecular Biology