Author

Patrick Mitchell

SLAC National Accelerator LaboratoryORCID 0000-0002-3458-6930Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Patrick Mitchell1 paper · University of Washington

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Amirhossein BakhtiiariiD· 1 shared Cathy HouiD· 1 shared Charlene Smith-GeateriD· 1 shared Chengbiao WuiD· 1 shared Cristina DanitaiD· 1 shared Els PardoniD· 1 shared Gong‐Her WuiD· 1 shared H. Ronald KabackiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Amirhossein BakhtiiariORCID

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2 papers

Recent·Most cited

Mobile barrier mechanisms for Na+-coupled symport in an MFS sugar transporter

Parameswaran Hariharan, Yuqi Shi, Satoshi Katsube, Katleen Willibal, Nathan D. Burrows, Patrick Mitchell, Amirhossein Bakhtiiari, Samantha Stanfield, Els Pardon, H. Ronald Kaback, Ruibin Liang, Jan Steyaert, Rosa Viner, Lan Guan

This study determines the structure and dynamics of a Na+-coupled sugar transporter, revealing how mobile barriers regulate substrate binding and release.

eLife · Feb 21, 2024Peer-reviewedMolecular Biology

CryoET Reveals Organelle Phenotypes in Huntington Disease Patient iPSC-Derived and Mouse Primary Neurons

Gong‐Her Wu, Charlene Smith-Geater, Jesús G. Galaz-Montoya, Yingli Gu, Sanket Rajan Gupte, Ranen Aviner, Patrick Mitchell, Joy Hsu, Ricardo Miramontes, Keona Q. Wang, Nicolette R. Geller, Cathy Hou, Cristina Danita, Lydia‐Marie Joubert, Michael F. Schmid, , Wah Chiu

This study uses cryoET and proteomics to identify mitochondrial and organelle abnormalities in HD models, showing potential for early diagnosis and therapy development.

Nature Communications · Feb 8, 2023Peer-reviewedNeuroscience