Ranen Aviner

Replicating without stress: a dengue replicon model reveals distinct host rewiring to accommodate persistence

This study uses a dengue replicon model to show how host pathways are rewired to support persistent RNA replication without stress responses.

ADAR1 Restricts Poliovirus Infection through dual disruption of translation initiation and protein coding

The paper identifies ADAR1 as a host factor that restricts poliovirus infection by editing viral RNA to disrupt translation initiation and introduce a coding error.

Robust virtual staining of landmark organelles

The paper develops robust virtual staining methods for cellular landmarks using deep learning, showing improved performance across cell types and imaging conditions.

CryoET Reveals Organelle Phenotypes in Huntington Disease Patient iPSC-Derived and Mouse Primary Neurons

This study uses cryoET and proteomics to identify mitochondrial and organelle abnormalities in HD models, showing potential for early diagnosis and therapy development.

A Comprehensive Enumeration of the Human Proteostasis Network. 1. Components of Translation, Protein Folding, and Organelle-Specific Systems

The paper defines and annotates 959 genes comprising the human proteostasis network, focusing on translation, protein folding, and organelle-specific systems.

Ribotoxic collisions on CAG expansions disrupt proteostasis and stress responses in Huntington's Disease

This study identifies ribotoxic collisions on CAG expansions as a mechanism causing proteostasis disruption and stress responses in Huntington's Disease.