Vakil Takhaveev

Click-chemistry-aided quantitation and sequencing of oxidized guanines and apurinic sites uncovers their transcription-linked strand bias in human cells

The paper improves click-code-seq for mapping DNA oxidation and depurination in human genomes, revealing strand bias in oxidized guanines and apurinic sites.

Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes

A synthetic RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux

The paper develops an RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux in yeast cells using FACS-seq screening.

Measuring glycolytic flux in single yeast cells with an orthogonal synthetic biosensor

The paper develops a synthetic biosensor to measure glycolytic flux in single yeast cells using fluorescence microscopy to identify metabolic subpopulations.