Author

Iwan Robert Evans

University of SheffieldORCID 0000-0002-3485-4456Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 4 Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Martin Peter ZeidleriD· 2 shared Albert C.M. OngiD· 1 shared Alexandra Rayson· 1 shared Amy Louise BrittleiD· 1 shared Charlotte E. Moss· 1 shared Dan J. HaymaniD· 1 shared Eleanor J. PhillipsiD· 1 shared Elliot BrooksiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersDevelopmental Biology

Martin Peter ZeidlerORCID

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4 papers

Recent·Most cited

Fisetin-mediated MYC restoration improves age-associated decline in macrophage function

Joshua V. Kimble, Charlotte E. Moss, Lilia S Hodge, Martha Clements, Alexandra Rayson, Kellie S Roberts, Ryan J. H. West, Iwan Robert Evans, Sheila Francis, Ilaria Bellantuono, Endre Kiss‐Toth, Heather L. Wilson

This study shows fisetin restores MYC expression in aged macrophages, improving their function and physical performance in older organisms.

bioRxiv · Jun 10, 2026 · PreprintImmunology

Expansion of Drosophila haemocytes using a conditional GeneSwitch driver affects larval haemocyte function, but does not modulate adult lifespan or survival from infection

Dan J. Hayman, Lola M. Morrin, Sudipta Halder, Eleanor J. Phillips, Mirre J. P. Simons, Iwan Robert Evans

This study expands and ablates Drosophila haemocytes using genetic tools, finding no effect on adult lifespan or infection resistance but observing pupal lethality in specific genetic backgrounds.

bioRxiv · Sep 17, 2024 · PreprintDevelopmental Biology

Macrophage subpopulation identity in Drosophila is modulated by apoptotic cell clearance and related signalling pathways

Elliot Brooks, Martin Peter Zeidler, Albert C.M. Ong, Iwan Robert Evans

This study identifies pathways modulating plasmatocyte subpopulations in Drosophila, showing that efferocytosis and Ecdysone receptor signaling shape their identity and function.

Frontiers in Immunology · Jan 12, 2024Peer-reviewedDevelopmental Biology

Identification of functionally-distinct macrophage subpopulations regulated by efferocytosis in Drosophila

Jonathon Alexis Coates, Amy Louise Brittle, Emma Louise Armitage, Martin Peter Zeidler, Iwan Robert Evans

The paper identifies functionally distinct plasmatocyte subpopulations in Drosophila regulated by efferocytosis and shows how their behavior and abundance can be modulated.

bioRxiv · Apr 17, 2020 · PreprintDevelopmental Biology