Mirre J. P. Simons

This study investigates the conservation of dietary restriction (DR) mechanisms across Drosophila species, finding phenotypic conservation but taxonomic specificity in genetic responses.

This study shows that suppressing the GCN2-ATF4 pathway extends lifespan in flies, while its activation reduces lifespan, revealing a dual role in aging.

This study shows that knocking down Rbp1, a fly spliceosome component, extends lifespan regardless of when the treatment is initiated.

This study investigates the genetic and environmental influences on body temperature during endothermy development in house sparrows using cross-fostered individuals.

The paper examines genetic and phenotypic correlations between survival and fecundity in house sparrows using long-term breeding data and multivariate animal models, finding no evidence of a trade-off.

This study expands and ablates Drosophila haemocytes using genetic tools, finding no effect on adult lifespan or infection resistance but observing pupal lethality in specific genetic backgrounds.

The paper shows that reaction norm variation explains inconsistent results in dietary restriction studies and highlights the need for personalized approaches in ageing research.