Author

Dan J. Hayman

University of SheffieldORCID 0000-0001-9125-1945Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Mirre J. P. SimonsiD· 3 shared Eleanor J. PhillipsiD· 1 shared Fumiaki ObataiD· 1 shared Gracie AdamsiD· 1 shared Iwan Robert EvansiD· 1 shared Lola M. Morrin· 1 shared Miriam S GötziD· 1 shared Sudipta HalderiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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3 shared papersPhysiology

Mirre J. P. SimonsORCID

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3 papers

Recent·Most cited

PhysiologyProceedings of the National Academy of SciencesPeer-reviewedApr 28, 2026

Suppression rather than activation of the integrated-stress-response (GCN2-ATF4) pathway extends lifespan in the fly

Miriam S Götz, Dan J. Hayman, Gracie Adams…·Mirre J. P. Simons

This study shows that suppressing the GCN2-ATF4 pathway extends lifespan in flies, while its activation reduces lifespan, revealing a dual role in aging.

DOI 10.1073/pnas.2518812123

Drosophilalong-read sequencing

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PhysiologyGeroSciencePeer-reviewedJan 9, 2026

Knockdown of the fly spliceosome component Rbp1(orthologue of SRSF1) extends lifespan

Dan J. Hayman, Mirre J. P. Simons

This study shows that knocking down Rbp1, a fly spliceosome component, extends lifespan regardless of when the treatment is initiated.

DOI 10.1007/s11357-025-02079-6

Drosophilaexperimental assay

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Developmental BiologybioRxivPreprintSep 17, 2024

Expansion of Drosophila haemocytes using a conditional GeneSwitch driver affects larval haemocyte function, but does not modulate adult lifespan or survival from infection

Dan J. Hayman, Lola M. Morrin, Sudipta Halder…·Iwan Robert Evans

This study expands and ablates Drosophila haemocytes using genetic tools, finding no effect on adult lifespan or infection resistance but observing pupal lethality in specific genetic backgrounds.

DOI 10.1101/2024.09.17.613448

Drosophilaexperimental assay

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