Stephanie Elaine Zimmer

This study uses volume EM to reveal the three-dimensional structure of desmosomes in epithelial cells and identifies novel features like discontinuities in the outer dense plaque.

This study shows that E-cadherin mediates ER recruitment to cell-cell junctions, forming ER-PMCS and integrating mechanical and lipid homeostasis.

This study identifies the biophysical properties of desmoglein-1 transmembrane domains as key determinants of lipid raft association and desmosome adhesive function.