Navaneetha Krishnan Bharathan

This paper presents a device for adapting upright light sheet fluorescence microscopy to image samples at air-liquid interface, demonstrating its use on three biological specimens.

This study uses volume EM to reveal the three-dimensional structure of desmosomes in epithelial cells and identifies novel features like discontinuities in the outer dense plaque.

This study shows that E-cadherin mediates ER recruitment to cell-cell junctions, forming ER-PMCS and integrating mechanical and lipid homeostasis.

The paper investigates the architectural arrangement of desmoplakin isoforms in desmosomes using dSTORM and shows that tail domain position correlates with rod length.

This study shows that PV autoantibodies trigger ER stress, leading to desmosome disruption and cell adhesion loss, and suggests ER stress as a therapeutic target.

This study shows that desmoplakin is essential for epidermal integrity and morphogenesis in Xenopus laevis embryos by regulating cell movement and differentiation.