Author

Christopher A. Piggott

University of California San DiegoORCID 0000-0002-3492-2105Unclaimed ORCID profile · follow to get notified of new preprints

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Genetics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Yishi JiniD· 2 shared Andrew D. ChisholmiD· 1 shared Antonina Jaroszewska· 1 shared Chris R. HackleyiD· 1 shared Dana T. ByrdiD· 1 shared Emma McIntyre· 1 shared Hannah Hirou· 1 shared Jocelin Chen· 1 shared

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2021-2024 · peak 1/yr

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10 top collaborators · 19 mutual co-author links

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2 shared papersGenetics

Yishi JinORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintApr 22, 2024

PACS-1 variant protein is aberrantly localized in C. elegans model of PACS1/PACS2 syndromes

Dana T. Byrd, Ziyuan Christina Han, Christopher A. Piggott, Yishi Jin

The paper investigates the effects of PACS1 and PACS2 variants on protein localization in C. elegans, showing altered localization and functional conservation with human proteins.

DOI 10.1101/2024.04.22.590644

C. elegansprotein structure

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GeneticsbioRxivPreprintAug 5, 2023

Methods and techniques enabling multi-kilobase long-range genomic rewrite/replace editing

Christopher A. Piggott, Laurentia V. Tjang, Selina Chen…·Chris R. Hackley

This paper introduces a method to rewrite large genomic regions using CRISPR/Cas9, enabling simultaneous editing of 7kb+ DNA sections without selection.

DOI 10.1101/2023.08.05.551844

humanexperimental assay

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GeneticsGeneticsPeer-reviewedApr 19, 2021

Caenorhabditis elegans junctophilin has tissue-specific functions and regulates neurotransmission with extended-synaptotagmin

Christopher A. Piggott, Zilu Wu, Stephen Nurrish…·Yishi Jin

This study investigates the tissue-specific functions of C. elegans JPH-1, showing its role in neurotransmission and muscle contraction, and its interaction with calcium channels.

14 citations

C. elegansexperimental assay

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