Jess Nithianantharajah

Gpr88 deletion impacts motivational control independently of striatal dopamine function

This study shows that Gpr88 deletion increases motivational drive in both sexes and impairs cost/benefit decision making in males, without affecting striatal dopamine function.

Postsynaptic neuroligin-1 mediates presynaptic endocytosis during neuronal activity

This study shows that postsynaptic neuroligin-1 influences presynaptic endocytosis during neuronal activity without affecting vesicle pools or exocytosis.

MicroRNA-210 Knockout Alters Dendritic Density and Behavioural Flexibility

This study shows that miR-210 knockout increases dendritic density and behavioural flexibility in mice by altering neuronal metabolism and oxidative stress.

Associative Learning and Motivation Differentially Requires Neuroligin-1 at Excitatory Synapses

This study shows that neuroligin-1 is essential for regulating distinct cognitive processes underlying decision-making, specifically affecting motivation and reward-cost trade-offs in mice.

Synaptic combinatorial molecular mechanisms generate repertoires of innate and learned behavior

The paper identifies synaptic protein combinations that underlie diverse innate and learned behaviors in mice, showing their role in behavioral repertoire expansion and disease susceptibility.