Woods Jon S

This study uses hPSCs to model MED with MATN3 mutations, revealing altered matrix organisation and upregulated cholesterol biosynthesis pathway.

The paper corrects a TYR variant associated with albinism in patient-derived iPSCs to create a model for studying pigmentation biology.

This study develops bioengineered blood vessels from iPSC-derived cells and silk fibroin-coated scaffolds, showing mechanical and structural properties similar to autologous grafts.

This study uses HNF1B mutant kidney organoids to reveal molecular and physiological defects in dysplastic kidney malformations and identify potential therapeutic targets.

This study shows that adding TTNPB and timed BMP2 to hPSC differentiation improves chondrogenesis, upregulating genes related to skeletal and cartilage development.

This paper develops an optogenetic system to control BMP signaling using blue light, enabling precise and dynamic activation in human cells.

This study uses patient-derived iPSCs to model Burn-McKeown Syndrome, revealing reduced TXNL4A expression causes splicing defects and impaired neural crest cell differentiation.

The paper identifies miR-140-3p as more abundant in human cartilage and shows its isomiRs have distinct functional targets.