Author

Margaret R. Smith-Oliver

Brigham and Women's HospitalORCID 0000-0002-3523-7150Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Ana Christina Garrido-CastroiD· 1 shared Deepa GautamiD· 1 shared Elisabeth M. BattinelliiD· 1 shared Emily M. ClarkeiD· 1 shared Giovanni Goggi· 1 shared Grace C. PetrarcaiD· 1 shared Harvey G. RowethiD· 1 shared Joanna BagińskaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ana Christina Garrido-CastroORCID

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1 paper

Recent·Most cited

Platelet-Mediated Suppression of T Cell Function Drives Immune Evasion in Triple Negative Breast Cancer through the P-Selectin / PSGL-1 Pathway

Margaret R. Smith-Oliver, Deepa Gautam, Emily M. Clarke, Grace C. Petrarca, Megan E. Sullivan, Giovanni Goggi, Miloš R. Spasić, Natalie Kane, Harvey G. Roweth, Ana Christina Garrido-Castro, Patricia Ellen Davenport, Joanna Bagińska, Sandra S. McAllister, Elisabeth M. Battinelli

This paper identifies a platelet-mediated immune evasion mechanism in TNBC via the P-selectin/PSGL-1 pathway, showing that blocking P-selectin can restore T-cell function and improve ICI response.

bioRxiv · Sep 12, 2025 · PreprintCancer Biology