Sandra S. McAllister

The paper constructs a single-cell peripheral immune atlas for Black and White women across breast disease states, identifying race-associated immune differences linked to chronic inflammation and immune aging in Black patients.

This paper identifies a platelet-mediated immune evasion mechanism in TNBC via the P-selectin/PSGL-1 pathway, showing that blocking P-selectin can restore T-cell function and improve ICI response.

This study identifies an estrogen receptor signaling program in HR+ breast cancer that suppresses immune responses by reducing T cell infiltration and HLA expression, suggesting therapeutic targets to enhance immunogenicity.