Author

Harvey G. Roweth

Brigham and Women's HospitalORCID 0000-0002-1100-8409Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Elisabeth M. BattinelliiD· 2 shared Albert-Ĺaszló BarabásiiD· 1 shared Ana Christina Garrido-CastroiD· 1 shared Andrew P. StoneiD· 1 shared Bernadette Anne Chua· 1 shared Deepa GautamiD· 1 shared Denís BarroniD· 1 shared Emily M. ClarkeiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

Elisabeth M. BattinelliORCID

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3 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedAug 13, 2026

Inhibition of RhoA-mediated secretory autophagy in megakaryocytes mitigates myelofibrosis in mice

Isabelle C. Becker, Siobhan Laken Branfield, María N. Barrachina…·Joseph E. Italiano

The paper shows that inhibiting RhoA-mediated secretory autophagy in megakaryocytes reduces cytokine secretion and fibrosis in a mouse model of myelofibrosis.

5 citationstop 1%

mousebulk RNA-seq

Cancer BiologybioRxivPreprintSep 12, 2025

Platelet-Mediated Suppression of T Cell Function Drives Immune Evasion in Triple Negative Breast Cancer through the P-Selectin / PSGL-1 Pathway

Margaret R. Smith-Oliver, Deepa Gautam, Emily M. Clarke…·Elisabeth M. Battinelli

This paper identifies a platelet-mediated immune evasion mechanism in TNBC via the P-selectin/PSGL-1 pathway, showing that blocking P-selectin can restore T-cell function and improve ICI response.

DOI 10.1101/2025.09.12.675650

mouseexperimental assay

BioinformaticsbioRxivPreprintAug 27, 2020

Network Medicine Framework Shows Proximity of Polyphenol Targets and Disease Proteins is Predictive of the Therapeutic Effects of Polyphenols

Ítalo Faria do Valle, Harvey G. Roweth, Michael W. Malloy…·Albert-Ĺaszló Barabási

The paper develops a network medicine framework to predict polyphenol therapeutic effects by analyzing the proximity of their protein targets to disease proteins in the human interactome.

3 citations

humanprotein structure