Author

Deepa Gautam

Brigham and Women's HospitalORCID 0000-0003-2437-6136Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Ana Christina Garrido-CastroiD· 1 shared Chen WengiD· 1 shared Dong Hoon LeeiD· 1 shared Elisabeth M. BattinelliiD· 1 shared Emily M. ClarkeiD· 1 shared Estelle CarminitaiD· 1 shared Giovanni Goggi· 1 shared Grace C. PetrarcaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Ana Christina Garrido-CastroORCID

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2 papers

Recent·Most cited

ImmunologyCell ReportsPeer-reviewedOct 30, 2026

MHC II-expressing bone marrow megakaryocytes are noncanonical antigen presenting cells and activate CD4+ T cells ex vivo

Virginia Camacho, Karen G. Wang, Pavel Hanč…·Kellie R. Machlus

The paper identifies MHC II-expressing bone marrow megakaryocytes as noncanonical antigen-presenting cells capable of activating CD4+ T cells and modulating immune responses.

1 citation

mouseproteomics

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Cancer BiologybioRxivPreprintSep 12, 2025

Platelet-Mediated Suppression of T Cell Function Drives Immune Evasion in Triple Negative Breast Cancer through the P-Selectin / PSGL-1 Pathway

Margaret R. Smith-Oliver, Deepa Gautam, Emily M. Clarke…·Elisabeth M. Battinelli

This paper identifies a platelet-mediated immune evasion mechanism in TNBC via the P-selectin/PSGL-1 pathway, showing that blocking P-selectin can restore T-cell function and improve ICI response.

DOI 10.1101/2025.09.12.675650

mouseexperimental assay

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