ImmunologybioRxivPreprint
Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury
Juliette Van Steenwinckel, Anne-Laure Schang, Michelle L Krishnan…·Pierre Gressens
The paper shows that reduced Wnt/β-catenin signaling in microglia of the developing brain causes pro-inflammatory activation and white matter injury, and that restoring this pathway can prevent these effects.
DOI 10.1101/334359