Stéphanie Ratté

Adaptation in somatosensory afferents improves rate and temporal coding of vibrotactile stimulus features

The paper shows adaptation in somatosensory afferents improves rate and temporal coding of vibrotactile stimulus features by modulating spiking in different ways.

Encoding of vibrotactile stimuli by mechanoreceptors in rodent glabrous skin

This study investigates the coding properties of low-threshold mechanoreceptors in rodent glabrous skin, showing their heterogeneity and how they encode vibrotactile stimuli through rate and temporal coding.

Equivalent excitability through different sodium channels and implications for the analgesic efficacy of selective drugs

The paper shows that nociceptors can achieve equivalent excitability through different sodium channel subtypes, challenging the effectiveness of subtype-selective analgesic drugs.

Paresthesia during spinal cord stimulation depends on synchrony of dorsal column axon activation

This study shows that kilohertz-frequency spinal cord stimulation activates dorsal column axons but causes asynchronous spiking, leading to paresthesia-free analgesia.

Minimal requirements for a neuron to co-regulate many properties and the implications for ion channel correlations and robustness

The paper shows that neurons can co-regulate multiple properties only if the number of adjustable ion channels exceeds the number of regulated properties, and that ion channel correlations arise when solution space dimensionality is low.

Spike initiation properties in the axon support high-fidelity signal transmission

The paper shows that the axon's spike initiation is transient and depends on depolarization rate and KV1 channels, implementing a high-pass filter for high-fidelity signal transmission.

Excitatory neurons are more disinhibited than inhibitory neurons by chloride dysregulation in the spinal dorsal horn

The paper shows excitatory neurons in the spinal dorsal horn are more disinhibited than inhibitory neurons due to chloride dysregulation, despite similar chloride levels, because they rely more on inhibition to balance strong excitation.