Author

Tariq A. Ganief

University of Cape TownORCID 0000-0002-3539-9328Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jonathan Michael BlackburniD· 2 shared Abhimanyu AbhimanyuiD· 1 shared Anca Flavia SavulescuiD· 1 shared C. Ronald KahniD· 1 shared David L. TabbiD· 1 shared Frank BrombacheriD· 1 shared Javan OkendoiD· 1 shared Kehilwe C. Nakedi· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Jonathan Michael BlackburnORCID

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2 papers

Recent·Most cited

Protein Kinase C δ: a critical hub regulating macrophage immunomodulatory functions during Mycobacterium tuberculosis infection

Rudranil Hazra, Mumin Ozturk, Nashied Peton, Tariq A. Ganief, Sibongiseni KL Poswayo, Robert P. Rousseau, S Naidoo, Shelby-Sara Jones, Anca Flavia Savulescu, Raymond M Moseki, Abhimanyu Abhimanyu, Nelita du Plessis, Jonathan Michael Blackburn, Musa M. Mhlanga, C. Ronald Kahn, , Suraj P. Parihar

This study investigates the role of PKCδ in macrophage immunomodulation during Mtb infection, finding that its deficiency leads to increased Mtb burden and exacerbated pathology.

bioRxiv · May 19, 2025 · PreprintImmunology

Phosphoproteomics reveals new insights into the role of PknG during the persistence of pathogenic mycobacteria in host macrophages

Seanantha S. Baros‐Steyl, Kehilwe C. Nakedi, Tariq A. Ganief, Javan Okendo, David L. Tabb, Nelson Cruz Soares, Jonathan Michael Blackburn

The paper uses phosphoproteomics to identify how PknG in mycobacteria reprograms macrophage function, revealing its role in evading immune clearance.

bioRxiv · Jan 19, 2021 · PreprintMolecular Biology