The C3HeB/FeJ Kramnik mouse as a model to investigate the efficacy of therapeutic tuberculosis interventions
Markus Depfenhart, Drieke Van der Merwe, Suraj P. Parihar…·Anne Grobler
This study evaluates the C3HeB/FeJ Kramnik mouse model for TB research by testing a novel Pheroid(R) formulation and highlights limitations in macrophage pathology and B-cell activity.