Circulating apoB-containing lipoproteins constituted blood-borne innate immune barrier limits ZIKV dissemination and congenital infection risk
Juncheng Chen, Dawei Lv, Wenlu Che, Yujie Chen, Yuanfei Zhu, Na Liu, Nihua Dong, Luhe Gan, Xinya Ji, Jiayu Qian, Guanglei Zhou, Yiming Tong, Jin Zhong, 肖明兵, Ralf F. W. Bartenschlager, Gang Long
The paper identifies apoB-containing lipoproteins as a blood-borne innate immune barrier that restricts ZIKV dissemination and congenital infection risk by blocking viral entry through PS receptor competition.
bioRxiv · Sep 16, 2026 · PreprintMicrobiology