Leslie Schwendimann

This study shows that C-sections combined with systemic inflammation worsen brain and gut issues in a preterm mouse model, increasing neurodevelopmental risks.

This study investigates the effects of perinatal inflammation on cerebellar development in a mouse model of encephalopathy of prematurity, finding unique microglia activation and type I interferon signaling dysregulation in the cerebellum.

The paper shows that reduced Wnt/β-catenin signaling in microglia of the developing brain causes pro-inflammatory activation and white matter injury, and that restoring this pathway can prevent these effects.