Author

John P. Konhilas

University of ArizonaORCID 0000-0002-3579-087XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Alexandra HartmaniD· 1 shared Amanda G. Chung· 1 shared Anna G. FigueroaiD· 1 shared Brian S. McKayiD· 1 shared Danielle A. BeckteliD· 1 shared Dominick Gherardini· 1 shared Eleni ConstantopoulosiD· 1 shared Jacob C. ZbeskoiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Alexandra HartmanORCID

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2 papers

Recent·Most cited

Modulating Cardiac-Gut Microbiome Interaction Post-Myocardial Infarction with Engineered Bacteria

Tushar Madaan, Michelle L. Nieman, Tushar Rakheja, Nabil Siddiqui, Dominick Gherardini, Mathieu G. Sertorio, Nitin S. Kamble, Shindu C. Thomas, Alexandra Hartman, Sheryl E. Koch, Lance Knipper, Vito A. Marino, Sakthivel Sadayappan, John N. Lorenz, John P. Konhilas, Nalinikanth Kotagiri

This study shows engineered bacteria can improve survival and cardiac function after myocardial infarction by enhancing gut barrier integrity and reducing inflammation.

bioRxiv · Jul 10, 2025 · PreprintSynthetic Biology

Liquefaction of the brain following stroke shares a similar molecular and morphological profile with atherosclerosis and mediates secondary neurodegeneration in an osteopontin dependent mechanism

Amanda G. Chung, Jennifer Beischel Frye, Jacob C. Zbesko, Eleni Constantopoulos, Megan I. Hayes, Anna G. Figueroa, Danielle A. Becktel, William A. Day, John P. Konhilas, Brian S. McKay, Thuy‐Vi V. Nguyen, Kristian P. Doyle

This paper compares ischemic inflammation in the heart and brain, finding a second inflammatory wave in the brain post-stroke linked to cholesterol crystals and osteopontin, which drives secondary neurodegeneration.

eNeuro · Sep 1, 2018Peer-reviewedNeuroscience