Mouse models of SYNGAP1-related intellectual disability
Yoichi Araki, Elizabeth E. Gerber, Kacey E. Rajkovich, Ingie Hong, Richard C. Johnson, Hey‐Kyoung Lee, Alfredo Kirkwood, Richard L. Huganir
This paper generates two knock-in mouse models with human SYNGAP1 mutations causing intellectual disability, showing reduced protein levels and recapitulating key disease features.
Proceedings of the National Academy of Sciences · Sep 5, 2023Peer-reviewedNeuroscience