Author

Timothy R. Gamache

Johns Hopkins UniversityORCID 0000-0002-7357-2857Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Ingie HongiD· 2 shared Richard L. HuganiriD· 2 shared Yoichi ArakiiD· 2 shared Alfredo KirkwoodiD· 1 shared Bian LiuiD· 1 shared Elizabeth E. GerberiD· 1 shared Hai TraniD· 1 shared Joo Heon ShiniD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Ingie HongORCID

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2 papers

Recent·Most cited

SynGAP regulates synaptic plasticity and cognition independent of its catalytic activity

Yoichi Araki, Kacey E. Rajkovich, Elizabeth E. Gerber, Timothy R. Gamache, Richard C. Johnson, Hai Tran, Bian Liu, Ingie Hong, Alfredo Kirkwood, Richard L. Huganir

This study shows SynGAP regulates synaptic plasticity and cognition through phase separation, not its catalytic activity.

bioRxiv · Aug 6, 2023 · PreprintNeuroscience

SynGAP splice isoforms differentially regulate synaptic plasticity and dendritic development

Yoichi Araki, Ingie Hong, Timothy R. Gamache, Shaowen Ju, Leonardo Collado‐Torres, Joo Heon Shin, Richard L. Huganir

This study shows that different SynGAP splice variants have distinct roles in synaptic plasticity and dendritic development through unique spatiotemporal expression and phase separation properties.

eLife · Jun 24, 2020Peer-reviewedNeuroscience