Cell BiologybioRxivPreprint
Patient-derived vascularized skin organoids unravel the role of systemic sclerosis fibroblasts in microvascular dysfunction.
Amandine Pitaval, Lara Jobeili, Caroline Welsch…·Walid Rachidi
This study uses patient-derived vascularized skin organoids to show that SSc fibroblasts drive microvascular dysfunction through secretome-induced fibrotic responses and crosstalk with endothelial cells.
DOI 10.64898/2025.12.03.691822