Author

Taro Q.P. Uyeda

Waseda UniversityORCID 0000-0002-3584-9499Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Kien Xuan NgoiD· 2 shared Akira NagasakiiD· 1 shared Han Gia NguyeniD· 1 shared Huong T. VuiD· 1 shared Kazumi HiranoiD· 1 shared Kenichi UmedaiD· 1 shared Minh-Nhat TrinhiD· 1 shared Motomichi DoiiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

Kien Xuan NgoORCID

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3 papers

Recent·Most cited

Structural basis for alpha-actinin inhibition of cooperative cofilin binding to actin filaments

Kien Xuan Ngo, Takashi Sumikama, Taro Q.P. Uyeda, Ngan Thi Phuong Le, Han Gia Nguyen, Rémi Vuillemot, Sergei Grudinin

This study investigates how alpha-actinin stabilizes actin filament structure, preventing cofilin-induced helical shortening and cooperative binding.

bioRxiv · Nov 16, 2025 · PreprintBiophysics

Actin Painting: a multicolor fluorescence staining method highlighting cell type-specific differences in the composition of filamentous actin architectures.

Akira Nagasaki, Saku T. Kijima, Yoichi Shinkai, Yukio Ohtsuka, Tomoyo Ochiishi, Y. Sasaki, Saori Hata, Kazumi Hirano, Yoshio Kato, Motomichi Doi, Taro Q.P. Uyeda

The paper introduces Actin Painting, a multicolor fluorescence staining method that distinguishes cell types by their unique F-actin architecture color patterns.

bioRxiv · Feb 5, 2025 · PreprintCell Biology

Deciphering the actin structure-dependent preferential cooperative binding of cofilin

Kien Xuan Ngo, Huong T. Vu, Kenichi Umeda, Minh-Nhat Trinh, Noriyuki Kodera, Taro Q.P. Uyeda

The paper investigates how cofilin binds preferentially to actin filaments by analyzing structural differences and their impact on binding and cluster formation.

eLife · Aug 2, 2024Peer-reviewedMolecular Biology