Author

Gonzalo Villanueva-Martín

Broad InstituteORCID 0000-0002-3585-4319Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1

Frequent Co-Authors

José Luís Callejas-RubioiD· 2 shared María Gutiérrez‐ArcelusiD· 2 shared Marialbert Acosta‐HerreraiD· 2 shared Alfredo Guillén del CastilloiD· 1 shared Andreea M. BujoriD· 1 shared Bernhard NieswandtiD· 1 shared Carmen Pilar Simeón‐AznariD· 1 shared Caroline Fromson· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersGenomics

José Luís Callejas-RubioORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sex-biased Fibroblast Subpopulations and Transcriptional Programs Reveal Mechanisms of Skin Lesion Development in Systemic Sclerosis

Chiranan Khantham, Inmaculada Rodriguez‐Martin, Martin Kerick, Gonzalo Villanueva-Martín, José Luis Callejas, Norberto Ortego‐Centeno, Alfredo Guillén del Castillo, Carmen Pilar Simeón‐Aznar, Ricardo Ruíz‐Villaverde, Eduardo Andrés‐León, J M Martin, Marialbert Acosta‐Herrera

The paper identifies sex-biased fibroblast subpopulations and transcriptional programs in systemic sclerosis, revealing sex-specific mechanisms of skin fibrosis.

bioRxiv · May 9, 2026 · PreprintGenomics

Transcriptional landscape of CD4+ T cells in Systemic Sclerosis

Gonzalo Villanueva-Martín, Gonzalo Borrego‐Yaniz, Marialbert Acosta‐Herrera, José Luís Callejas-Rubio, Norberto Ortego, Norbert Mages, Stefan T. Boerno, María Gutiérrez‐Arcelus, Javier Martin, Lara Bossini‐Castillo

This study uses scRNA-seq to characterize CD4+ T cell subpopulations in SSc patients, identifying interferon-driven activation, reduced TNF signaling, and altered Treg states.

bioRxiv · Mar 19, 2026 · PreprintGenetics

A GPVI-platelet-neutrophil-NET axis drives systemic sclerosis

Roxane Darbousset, Gonzalo Villanueva-Martín, Julia Kuehn, Stefano Navarro, Spoorthi Balu, Dhruv Miglani, Eilish Dillon, Caroline Fromson, Leetah Senkpeil, Mehreen Elahee, Pierre‐André Jarrot, Sydney B. Montesi, Deepak A. Rao, Jerry L. Ware, Denisa D. Wagner, , Peter Andrija Nigrovic

This study identifies a GPVI-platelet-neutrophil-NET axis that drives systemic sclerosis fibrosis and presents it as a therapeutic target.

bioRxiv · Jan 21, 2025 · PreprintImmunology