Vγ1+ γδ T cell-derived IL-4 initiates CD8 T cell immunity
Shirley Le, Nick Dooley, Declan Murphy…·Lynette Beattie
The paper shows Vγ1+ γδ T cells produce IL-4 to activate DC and CD8 T cells, enhancing immunity against Plasmodium.
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The University of MelbourneORCID 0000-0002-3599-2455Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Shirley Le, Nick Dooley, Declan Murphy…·Lynette Beattie
The paper shows Vγ1+ γδ T cells produce IL-4 to activate DC and CD8 T cells, enhancing immunity against Plasmodium.
Thomas N. Burn, Jan Schröder, Luke C. Gandolfo…·Laura K. Mackay
This study distinguishes tissue-resident memory (TRM) and exhausted T (TEX) cells in tumors by analyzing their antigen reactivity, clonality, and functional outcomes.
Ramyar Molania, Momeneh Foroutan, Johann A. Gagnon-Bartsch…·Terence Paul Speed
This paper identifies major sources of unwanted variation in cancer RNA-seq data and proposes a novel method to remove them using pseudo-replicates of pseudo-samples.
Necla Koçhan, G. Yazgı Tütüncü, Gordon K. Smyth…·Göknur Giner
The paper introduces qtQDA, a classification method for RNA-seq data that uses quantile transformation and regularized QDA, showing good performance on real datasets.