Laura K. Mackay

This study identifies tissue-resident memory T cells in the human cornea and shows their abundance is influenced by age, sex, and systemic immune activation.

The paper investigates how immune responses to infection affect peripheral sympathetic neuron functions, finding that cytokines and interferons alter nerve growth and neuron excitability.

This study identifies GCNT2 as a glycosylation-dependent checkpoint that restrains intestinal intra-epithelial lymphocyte (IEL) activation by modifying CD45 and dampening TCR signaling.

The paper shows Vγ1+ γδ T cells produce IL-4 to activate DC and CD8 T cells, enhancing immunity against Plasmodium.

This study shows that antigen encounter in the epidermis enhances TRM persistence and proliferation through TGF{beta} signaling and TGF{beta}RIII expression.

The paper identifies transcriptional modules and cytokine signaling pathways that drive functional heterogeneity in T follicular helper cells across different infections.

This study distinguishes tissue-resident memory (TRM) and exhausted T (TEX) cells in tumors by analyzing their antigen reactivity, clonality, and functional outcomes.

This study shows that purinergic signaling via ARTC2 and P2RX7 regulates the survival and function of unconventional T cells, affecting IFN-γ and IL-4 production.