Denny Joseph Manual Kollareth

This study identifies YAP/TAZ signaling in endothelial cells as a key mediator of abdominal aortic aneurysm formation and shows that pharmacological inhibition reduces AAA progression.

This study shows that inhibiting ferroptosis with liproxstatin-1 reduces AAA formation by decreasing inflammation and aortic remodeling in mice.

This study shows that LxA4/FPR2 signaling reduces ferroptosis in alveolar epithelial cells via NRF2 activation, protecting against lung ischemia-reperfusion injury.

This study shows that MerTK-dependent efferocytosis by monocytic-MDSCs reduces post-lung transplant ischemia-reperfusion injury.