Author

Zayd Tippu

Royal Marsden NHS Foundation TrustORCID 0000-0002-3602-0770Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Anne-Laure CattiniD· 2 shared Annika FendleriD· 2 shared Daqi DengiD· 2 shared Fiona ByrneiD· 2 shared Hugang FengiD· 2 shared Jiahao Wang· 2 shared Omar Bouricha· 2 shared Samra TurajliciD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Anne-Laure CattinORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Distinct functions of PBRM1 and BAP1 reconcile the course of kidney cancer evolution and disease progression

Daqi Deng, Hugang Feng, Annika Fendler, Yuliia Dovga, Fiona Byrne, Charlotte Spencer, Alice C. Martin, Ángel Fernández-Sanromán, Omar Bouricha, Scott T.C. Shepherd, Hongchang Fu, Anne-Laure Cattin, Husayn Ahmed Pallikonda, Irene Lobón, Kevin Mulder, , Samra Turajlic

This study identifies distinct molecular programs in PBRM1- and BAP1-driven ccRCC, explaining their different evolutionary trajectories and clinical outcomes.

bioRxiv · May 3, 2026 · PreprintCancer Biology

Genome-wide Chromosome-specific Aneuploidy Engineering and Phenotypic Characterization with CRISPR-Taiji

Hugang Feng, Daqi Deng, Rashmi Dahiya, Libin Wang, Jingkun Zeng, Benjy J.Y. Tan, Fiona Byrne, Scott T.C. Shepherd, Jiahao Wang, Sarah C. Johnson, Alison Harrod, Karen A. Lane, Annika Fendler, Anne-Laure Cattin, Zayd Tippu, , Samra Turajlic

The paper introduces CRISPR-Taiji to engineer chromosome-specific aneuploidy and characterizes its transcriptomic effects, linking aneuploidy to ccRCC phenotypes.

bioRxiv · Apr 25, 2025 · PreprintGenomics