Author

Emily J. Sherman

University of MichiganORCID 0000-0002-3632-271XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:perturbation response prediction· 2

Frequent Co-Authors

Brian T. EmmeriD· 2 shared Cristen J. WilleriD· 2 shared Sarah E. GrahamiD· 2 shared Andrew A. KennedyiD· 1 shared Andrew W. TaiiD· 1 shared Carmen MirabelliiD· 1 shared Christiane E. WobusiD· 1 shared David GinsburgiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenomics

Brian T. EmmerORCID

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2 papers

Recent·Most cited

Identification of ACE2 modifiers by CRISPR screening

Emily J. Sherman, Carmen Mirabelli, Vi T. Tang, Taslima Gani Khan, Andrew A. Kennedy, Sarah E. Graham, Cristen J. Willer, Andrew W. Tai, Jonathan Z. Sexton, Christiane E. Wobus, Brian T. Emmer

This study uses CRISPR screening to identify 35 genes that modify ACE2 surface abundance in HuH7 cells, revealing regulators of ACE2 expression and their impact on SARS-CoV-2 susceptibility.

bioRxiv · Jun 10, 2021 · PreprintGenomics

Genome-scale CRISPR screening for modifiers of cellular LDL uptake

Brian T. Emmer, Emily J. Sherman, Paul J. Lascuna, Sarah E. Graham, Cristen J. Willer, David Ginsburg

The paper uses genome-scale CRISPR screening to identify genetic modifiers of LDL uptake in hepatocytes, finding several new genes involved in this process.

PLoS Genetics · Jan 29, 2021Peer-reviewedGenomics