Vi T. Tang

This study identifies conventionally and unconventionally secreted proteins from HUVECs under inflammatory stress, revealing novel UCPS cargo and their functional roles.

The paper shows that SAR1A and SAR1B paralogs have overlapping functions in mice, with SAR1A compensating for SAR1B deficiency.

This study identifies PROX1 and CHD7 as regulators of LDL uptake, with PROX1 directly enhancing LDLR expression and CHD7 acting through an LDLR-independent mechanism.

This study uses CRISPR screening to identify 35 genes that modify ACE2 surface abundance in HuH7 cells, revealing regulators of ACE2 expression and their impact on SARS-CoV-2 susceptibility.