Author

Carmen Mirabelli

University of LübeckORCID 0000-0002-4785-5482Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Christiane E. WobusiD· 2 shared Andrew A. KennedyiD· 1 shared Andrew W. TaiiD· 1 shared Brian T. EmmeriD· 1 shared Cristen J. WilleriD· 1 shared Emily J. ShermaniD· 1 shared Heike Marlene Laschin· 1 shared Jonathan Z. SextoniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Christiane E. WobusORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Polyamine depletion inhibits norovirus infection by blocking virus-induced apoptosis

Maryna Chaika, Heike Marlene Laschin, Marina Pekelis, Carmen Mirabelli, Sandra Niendorf, Christiane E. Wobus, Stefan Taube

This study shows polyamine depletion inhibits norovirus infection by blocking virus-induced apoptosis and virion release in both human and murine systems.

bioRxiv · Sep 14, 2025 · PreprintMicrobiology

Identification of ACE2 modifiers by CRISPR screening

Emily J. Sherman, Carmen Mirabelli, Vi T. Tang, Taslima Gani Khan, Andrew A. Kennedy, Sarah E. Graham, Cristen J. Willer, Andrew W. Tai, Jonathan Z. Sexton, Christiane E. Wobus, Brian T. Emmer

This study uses CRISPR screening to identify 35 genes that modify ACE2 surface abundance in HuH7 cells, revealing regulators of ACE2 expression and their impact on SARS-CoV-2 susceptibility.

bioRxiv · Jun 10, 2021 · PreprintGenomics