Robert P. Hausinger

This paper demonstrates a modular platform for enzyme encapsulation using bacterial microcompartment shells, showing successful activity and stability for multiple enzymes.

This paper describes the self-assembly of SpyTag-fused bacterial microcompartment trimers into macroscopic protein materials with functional properties in both solution and dried states.

The paper investigates two LarA-like enzymes lacking a catalytic histidine residue, solving their structures and revealing a novel octameric assembly and active site residues involved in carbohydrate metabolism.

This study reports three high-resolution structures of a broad-spectrum LarA enzyme, revealing substrate binding mode and residues critical for substrate recognition and catalysis.

This paper evaluates an ancestral sequence reconstruction-informed data augmentation strategy for improving protein sequence generation and representation learning, showing improved thermostability in generated variants.