Author

Valérie Najburg

Institut PasteurORCID 0000-0002-3683-3069Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metagenomics· 1

Frequent Co-Authors

Anastassia V. KomarovaiD· 2 shared Frédéric TangyiD· 2 shared Aleksandr BarinoviD· 1 shared Andrea Di GioacchinoiD· 1 shared Atousa Arbabian· 1 shared Benjamin D. GreenbaumiD· 1 shared Bernadette Brzezicha· 1 shared Chantal CombredetiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Anastassia V. KomarovaORCID

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2 papers

Recent·Most cited

Disabling a key viral innate immunity antagonist converts measles vaccine into RIG-I-driven cancer immunotherapy

Aleksandr Barinov, Heidy Vera-Peralta, Joëlle S. Nader, Valérie Najburg, Chantal Combredet, Atousa Arbabian, Ségolène Gracias, Phanramphoei Namprachan Frantz, Roseline Vibert, Eddy Simard, Marie Coateval, Daniel Pouliquen, Tacien Petithomme, Matthieu Prot, Etienne Simon‐Lorière, , Frédéric Tangy

This paper modifies a measles vaccine by removing a viral protein to create a cancer immunotherapy that activates the immune system via RIG-I signaling, leading to tumor regression in multiple models.

bioRxiv · Oct 3, 2025 · PreprintImmunology

sgDI-tector: defective interfering viral genome bioinformatics for detection of coronavirus subgenomic RNAs

Andrea Di Gioacchino, Rachel Legendre, Yannis Rahou, Valérie Najburg, Pierre Charneau, Benjamin D. Greenbaum, Frédéric Tangy, Sylvie van der Werf, Simona Cocco, Anastassia V. Komarova

sgDI-tector detects and quantifies subgenomic RNAs in SARS-CoV-2 NGS data, identifying a ranked set of sgRNAs and comparing their levels to defective interfering viral genomes.

RNA · Dec 22, 2021Peer-reviewedBioinformatics