Variant-specific spike conformational dynamics shape memory B cell selection during recall
Manon Broutin, Aurélien Sokal, Alice Dejoux, Delphine Planas, Matthias A. Vanderkerken, Ignacio Fernández, Imane Azzaoui, Alexis Vandenberghe, Manon Charlet, Atousa Arbabian, Jérôme Megret, Lamine Touré, Cyril Planchais, Laurence Berard, Tabassome Simon, , Pascal Chappert
The paper shows that variant-specific spike conformational dynamics influence memory B cell recruitment and antibody responses during vaccination.
bioRxiv · Jul 20, 2026 · PreprintImmunology