Author

Frederik Cleeren

KU LeuvenORCID 0000-0002-3692-1608Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Bart De StrooperiD· 1 shared Christopher CawthorneiD· 1 shared Guy M BormansiD· 1 shared Jarne Clerckx· 1 shared Maarten DewildeiD· 1 shared Marie‐Lynn CuypersiD· 1 shared Nick GeukensiD· 1 shared Simon LeekensiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

Bart De StrooperORCID

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1 paper

Recent·Most cited

Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein

Marie‐Lynn Cuypers, Tom Jaspers, Jarne Clerckx, Simon Leekens, Christopher Cawthorne, Guy M Bormans, Frederik Cleeren, Nick Geukens, Bart De Strooper, Maarten Dewilde

This paper demonstrates that binding antibodies to myelin oligodendrocyte glycoprotein (MOG) significantly increases their brain half-life when combined with transferrin receptor (TfR) mediated transport.

Fluids and Barriers of the CNS · Jan 30, 2025Peer-reviewedPharmacology & Toxicology