Author

Jean-Samuel Dupré

F. Hoffmann-La Roche AGORCID 0000-0002-3708-0425Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

J. Gray CampiD· 3 shared Irineja Cubela· 2 shared Julian SchereriD· 2 shared Laura Gaspa-ToneuiD· 2 shared Adrian M. Filip· 1 shared Andreas R. HierlemanniD· 1 shared Barbara TreutleiniD· 1 shared Barbora LavickovaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

J. Gray CampORCID

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Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 11, 2026

A perturbation atlas of mouse neural organoids resolves macroglial reactivity and nominates drivers of degeneration

Jean-Samuel Dupré, Marina Signer, Jyoti Rao…·J. Gray Camp

This study creates a perturbation atlas of mouse neural organoids to understand macroglial reactivity and identify drivers of degeneration.

DOI 10.64898/2026.10.09.757894

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PathologyCell Reports MethodsPeer-reviewedApr 23, 2026

High-throughput histopathology for complex in vitro models

Marius F. Harter, Elisa D’Arcangelo, Julien Aubert…·Nikolche Gjorevski

This paper introduces a high-throughput histopathology workflow for complex in vitro models using 3D-printed histomolds, enabling efficient processing and analysis of multiple samples.

7 citationstop 4%

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Developmental BiologyNature NeurosciencePeer-reviewedJun 24, 2024

Single-cell epigenomic reconstruction of developmental trajectories in human neural organoid systems from pluripotency

Fides Lea Zenk, Jonas Simon Fleck, Sophie Martina Johanna Jansen…·Barbara Treutlein

The paper reconstructs epigenomic trajectories in human neural organoids from pluripotency to terminal cell states using single-cell histone modification profiling.

52 citationstop 2%

humanscATAC-seq

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