Author

Elisa D’Arcangelo

F. Hoffmann-La Roche AGORCID 0000-0002-9147-0109Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Irineja Cubela· 2 shared J. Gray CampiD· 2 shared Lauriane CaboniD· 2 shared Matthias P. LütolfiD· 2 shared Ryo Okuda· 2 shared Adrian M. Filip· 1 shared Andreas Wilfer· 1 shared Anne EugsteriD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersPathology

Irineja Cubela

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Targeting poorly differentiated thyroid cancer with bispecific antibodies and CAR T cells from the human anti-TSHR autoantibody repertoire

Claudia Fischer, Anne Eugster, Brenda Besemer, Mélanie Buchi, Marcus Bauer, Christoph Schultheiß, Elisa D’Arcangelo, Filip Filipsky, Claudia Wickenhauser, Andreas Wilfer, Kerstin Lorenz, Jens Jakscha, Laurent Müller, Roswitha Köberle-Wührer, Benjamin Kasenda, , Mascha Binder

This paper explores using anti-TSHR autoantibodies to create bispecific antibodies and CAR T cells for treating poorly differentiated thyroid cancer, showing potent in vitro and in vivo activity.

bioRxiv · Oct 20, 2026 · PreprintCancer Biology

Human lung explants as a predictive platform for evaluating the on-target, off-tumor toxicity of T cell bispecifics

Manuel Tschan, Tania Jetzer, Melanie Obenloch, Annika Blank, Carmen S. M. Yong, Nitya Nair, Lauriane Cabon, Elisa D’Arcangelo, Matthias P. Lütolf

This paper establishes a human lung explant model to quantify T cell bispecifics' on-target, off-tumor toxicity by measuring T cell activation and epithelial cell killing.

iScience · Sep 26, 2026Peer-reviewedCancer Biology

High-throughput histopathology for complex in vitro models

Marius F. Harter, Elisa D’Arcangelo, Julien Aubert, Barbora Lavickova, Charles A. Havnar, Bilgenaz Stoll, Irineja Cubela, Adrian M. Filip, Laura Gaspa-Toneu, Julian Scherer, Evdoxia Karagkiozi, Jean-Samuel Dupré, Rubén López-Sandoval, Rebecca Hsia, Leah M. Norona, , Nikolche Gjorevski

This paper introduces a high-throughput histopathology workflow for complex in vitro models using 3D-printed histomolds, enabling efficient processing and analysis of multiple samples.

Cell Reports Methods · Apr 23, 2026Peer-reviewedPathology

An integrated platform for high-throughput phenospace learning of 3D multilineage organoid systems

Ryo Okuda, Christoph Harmel, Quan Xu, Héloïse Mary, Philip Schulz, Linda Steinacher, Elisa D’Arcangelo, Bruno Gjeta, Marina Signer, Irineja Cubela, Marc Bickle, Matthias P. Lütolf, Lauriane Cabon, Ilya Lukonin, J. Gray Camp

The paper introduces a platform for high-throughput spatial phenotyping of multilineage organoids, identifying pathway modulators and treatment strategies for PDAC.

bioRxiv · Nov 27, 2025 · PreprintCancer Biology