Author

Adrian M. Filip

F. Hoffmann-La Roche AG

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:spatial domain detection· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Irineja Cubela· 3 shared Marius F. HarteriD· 3 shared Nikolche GjorevskiiD· 3 shared Barbora LavickovaiD· 2 shared J. Gray CampiD· 2 shared Julien AubertiD· 2 shared Kristina KromeriD· 2 shared Laura Gaspa-ToneuiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

Irineja Cubela

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Modular engineered colorectal tumor microenvironments for immuno-oncology research and drug development

Adrian M. Filip, Barbora Lavickova, Aurélie Hérault, Irineja Cubela, Benjamin Ehret, Esther Danenberg, Michelle C Daniel, Stéphane Chevrier, Mairene Coto‐Llerena, Giulia Protti, Sören Müller, Sophie Jansen, Kristina Kromer, Marius F. Harter, Sofia Tsiepa, , Nikolche Gjorevski

This paper introduces SHOCOs, a modular system using patient-derived colorectal tumor organoids and fibroblasts to model tumor microenvironments, showing improved immune response and stromal effects on therapy.

bioRxiv · Sep 23, 2026 · PreprintCancer Biology

High-throughput histopathology for complex in vitro models

Marius F. Harter, Elisa D’Arcangelo, Julien Aubert, Barbora Lavickova, Charles A. Havnar, Bilgenaz Stoll, Irineja Cubela, Adrian M. Filip, Laura Gaspa-Toneu, Julian Scherer, Evdoxia Karagkiozi, Jean-Samuel Dupré, Rubén López-Sandoval, Rebecca Hsia, Leah M. Norona, , Nikolche Gjorevski

This paper introduces a high-throughput histopathology workflow for complex in vitro models using 3D-printed histomolds, enabling efficient processing and analysis of multiple samples.

Cell Reports Methods · Apr 23, 2026Peer-reviewedPathology

Modeling host-microbe interactions in immunocompetent engineered human gut tissues

Rubén López-Sandoval, Marius F. Harter, Qianhui Yu, Laura Gaspa-Toneu, Irineja Cubela, Kristina Kromer, Julien Aubert, Adrian M. Filip, Lukas Kaltenbach, Marina Bellavista, Ninouk Akkerman, Yannik Bollen, Salem Munteanu, Justine Fidelin, Angélique Augustin, , J. Gray Camp

The paper develops engineered human gut tissues to study host-microbe interactions and identifies an epithelial gene regulatory network in response to Salmonella Typhimurium infection.

bioRxiv · May 2, 2025 · PreprintBioengineering