Bérangère Lombard

This study shows that translational control of 53BP1 mRNA regulates adaptive mutability in melanoma cells, and targeting eIF4A reduces resistance to BRAF/MEK inhibitors.

The paper examines chromatin regulation in brown algae, showing loss of canonical silencing systems and emergence of H3K79 methylation as a repressive mechanism.

This study identifies ORF1p interactions with proteins and chromatin in neurons, showing its role in gene regulation and neurite morphology.

The paper identifies glutamate methylation as a novel histone modification in diatoms and other organisms, showing structural effects on nucleosome stability.

This study identifies a metabolism-chromatin axis that regulates ribosome heterogeneity in Plasmodium falciparum during host-to-vector transmission.

This study harmonizes quality controls across proteomics core facilities to improve data comparability and reliability through a 4-year longitudinal dataset and common processing software.

The paper investigates LINE-1 ORF1p protein and RNA expression in mouse and human brains, finding increased levels with aging and neuron-specific expression patterns.

This paper shows that the Legionella pneumophila effector LegK1 suppresses RNA silencing by interacting with Argonaute proteins and activating NF-κB signaling, enhancing bacterial virulence.

This study identifies RACK1 as a repressor of KIR4.1 translation in astrocytes, showing its role in regulating neuronal activity through modulation of KIR4.1 expression.

The paper identifies 47 histone PTMs in the brown alga Ectocarpus, including a novel mark, and shows their stable patterns through the life cycle and association with gene expression.

The paper identifies the role of the MutLγ-Exo1 complex in meiotic crossover formation by showing Exo1 recruits Cdc5 to activate MutLγ and highlights its spatial regulation near DSB hotspots.