Author
Sean A. Murphy
Johns Hopkins UniversityORCID 0000-0003-1960-2194Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 42 mutual co-author links6 papers
Recent·Most cited
- Developmental BiologybioRxivPreprintDOI 10.64898/2026.07.25.740735
- Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewed
Cardiac progenitors auto-regulate second heart field cell fate via Wnt secretion
Matthew Miyamoto, Suraj Kannan, Matthew J. Anderson…·Chulan Kwon
The paper identifies cardiac progenitors as a source of Wnts that regulate second heart field development through secretion, using genetic manipulation and single-cell RNA sequencing in mice.
- BioinformaticsJournal of Computational BiologyPeer-reviewed
Cross-organ transcriptomic comparison reveals universal factors during maturation
Sandeep Kambhampati, Sean A. Murphy, Hideki Uosaki, Chulan Kwon
The paper identifies universal gene pathways and regulators involved in organ maturation across four mouse tissues.
3 citations - Developmental BiologyBiochemical and Biophysical Research CommunicationsPeer-reviewed
Noncanonical Notch signals have opposing roles during cardiac development
Matthew Miyamoto, Peter Andersen, Edrick Sulistio…·Chulan Kwon
This study shows noncanonical Notch signaling has stage-specific roles in cardiac development, inhibiting early heart formation but promoting later growth.
10 citations - Developmental BiologyNature CommunicationsPeer-reviewed
PGC1/PPAR Drive Cardiomyocyte Maturation through Regulation of Yap1 and SF3B2
Sean A. Murphy, Matthew Miyamoto, Anaïs Kervadec…·Chulan Kwon
This study identifies PGC1/PPAR signaling and its regulators Yap1 and SF3B2 as key drivers of cardiomyocyte maturation through single-cell transcriptomic analysis across neonatal to adult hearts.
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