Alyssa B. Evans

This study identifies mitochondrial energy production as a key host factor mediating cell death from CSG orthobunyaviruses and shows that reducing energy production can protect cells from viral infection.

This study identifies that LACV neurovirulence is a complex trait mediated by proteins on all three genome segments, with the M and S segments being primary drivers.

The paper develops a mix-and-match reverse genetics system for orthobunyaviruses to study genetic factors in neurological disease.