Craig Martens

The paper designs a synthetic consensus IFN-β for bats that induces IFN-I signaling across diverse bat species, enabling study of antiviral immunity.

This study identifies NONO as a host factor that epigenetically regulates DPP4 expression, facilitating MERS-CoV replication by modulating histone modifications at the DPP4 locus.

This study identifies NONO as a critical facilitator of antiviral innate immune response by promoting chromatin accessibility and IFN-I/ISG expression.

This study identifies that LACV neurovirulence is a complex trait mediated by proteins on all three genome segments, with the M and S segments being primary drivers.

This study compares the tissue tropism of two HPAI H5N1 isolates in mice, finding that the bovine isolate replicates in the brain and causes more neurotropism and inflammation than the human isolate.

This study shows Jamaican fruit bats can support EBOV replication and shedding but not MARV, due to differences in viral entry and IFN-I signaling suppression.

This study identifies hypoxia as a key driver of immune dysfunction in TB granulomas, correlating with bacterial persistence.

This study identifies RBM4 as a post-transcriptional regulator of endogenous retrovirus (ERV) expression using computational analysis and experimental validation.