Author

Linda L. Garthwaite

Victor Chang Cardiac Research InstituteORCID 0000-0002-3784-0308Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Amy Nguyen· 1 shared Berwyck L. J. PoadiD· 1 shared Eileen Ding· 1 shared Felicia Hansen· 1 shared J. Lising· 1 shared Jan Philipp MenzeliD· 1 shared Konstantina Harellis· 1 shared Laura L. Y. Choong· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Amy Nguyen

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1 paper

Recent·Most cited

Targeting de novo lipogenesis improves gemcitabine efficacy in pancreatic ductal adenocarcinoma

Sarah E. Hancock, Linda L. Garthwaite, Konstantina Harellis, Michael Susetio, Eileen Ding, Laura L. Y. Choong, Osvaldo Contreras, Amy Nguyen, J. Lising, Felicia Hansen, Puttandon Wongsomboon, Jan Philipp Menzel, Berwyck L. J. Poad, Todd W. Mitchell, Stephen J. Blanksby, Nigel A. Turner

This study identifies de novo lipogenesis as a mechanism of gemcitabine resistance in PDAC and shows that targeting lipid synthesis enzymes enhances treatment efficacy.

bioRxiv · Dec 18, 2024 · PreprintCancer Biology