Author

Todd W. Mitchell

University of WollongongORCID 0000-0002-1372-9963Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:yeast· 1

Frequent Co-Authors

Alan T. MaccaroneiD· 1 shared Amy Nguyen· 1 shared Anton I.P.M. de KrooniD· 1 shared Berwyck L. J. PoadiD· 1 shared Céline KelsoiD· 1 shared Eileen Ding· 1 shared Felicia Hansen· 1 shared J. Lising· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Alan T. MaccaroneORCID

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2 papers

Recent·Most cited

Targeting de novo lipogenesis improves gemcitabine efficacy in pancreatic ductal adenocarcinoma

Sarah E. Hancock, Linda L. Garthwaite, Konstantina Harellis, Michael Susetio, Eileen Ding, Laura L. Y. Choong, Osvaldo Contreras, Amy Nguyen, J. Lising, Felicia Hansen, Puttandon Wongsomboon, Jan Philipp Menzel, Berwyck L. J. Poad, Todd W. Mitchell, Stephen J. Blanksby, Nigel A. Turner

This study identifies de novo lipogenesis as a mechanism of gemcitabine resistance in PDAC and shows that targeting lipid synthesis enzymes enhances treatment efficacy.

bioRxiv · Dec 18, 2024 · PreprintCancer Biology

Temperature adaptation of yeast phospholipid molecular species at the acyl chain positional level

Céline Kelso, Alan T. Maccarone, Anton I.P.M. de Kroon, Todd W. Mitchell, Mike F. Renne

This study examines how yeast adjusts phospholipid molecular species at the acyl chain positional level in response to temperature changes using mass spectrometry.

FEBS Letters · Dec 13, 2024Peer-reviewedBiochemistry