Author

Siqi Lai

Peter MacCallum Cancer CentreORCID 0000-0002-3845-1961Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:trajectory inference· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Adrienne Margaret FlanaganiD· 1 shared Amy L. BowesiD· 1 shared Andrew R. GreeniD· 1 shared Andrew R. LynchiD· 1 shared Annelien VerfaillieiD· 1 shared Charles SwantoniD· 1 shared David J. ByrneiD· 1 shared Dorothea LescheiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

Adrienne Margaret FlanaganORCID

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2 papers

Recent·Most cited

Cancer BiologyThe Journal of PathologyPeer-reviewedOct 30, 2025

Phylogenetic analysis of paired breast carcinomas identifies genetic events associated with clonal recurrence and invasive progression

Tanjina Kader, Maia Zethoven, Sakshi Mahale…·Kylie L. Gorringe

The paper analyzes paired breast carcinomas to determine if recurrences are clonal or new tumors, finding 7% are non-clonal by whole exome sequencing.

2 citations

humanwhole-exome sequencing

𝕏 PostBluesky

GenomicsCancer DiscoveryPeer-reviewedJun 28, 2024

The history of chromosomal instability in genome doubled tumors

Toby M. Baker, Siqi Lai, Andrew R. Lynch…·Peter Van Loo

This paper introduces GRITIC, a method to time genomic gains in tumors, finding that copy number gains often accumulate after genome duplication.

21 citationstop 4%

humanbulk RNA-seq

𝕏 PostBluesky