Author

Amy L. Bowes

Maidstone HospitalORCID 0000-0001-9506-5023Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Adrienne Margaret FlanaganiD· 1 shared Alexandrine CarminatiiD· 1 shared Andrew R. LynchiD· 1 shared Annelien VerfaillieiD· 1 shared Benjamin ShumiD· 1 shared Charles SwantoniD· 1 shared Erik A. SahaiiD· 1 shared Giovanni GiangrecoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Adrienne Margaret FlanaganORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 23, 2025

Cooperative and antagonistic interactions between sub-clones favour the co-existence of multiple resistance mechanisms in melanoma

Karin Schlegelmilch, Viola Hollek, Steven Hooper…·Erik A. Sahai

This study shows that cooperative and antagonistic interactions between sub-clones in melanoma allow multiple resistance mechanisms to coexist, and identifies GSK-J4 as a potential therapeutic target.

DOI 10.1101/2025.10.23.684170

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsCancer DiscoveryPeer-reviewedJun 28, 2024

The history of chromosomal instability in genome doubled tumors

Toby M. Baker, Siqi Lai, Andrew R. Lynch…·Peter Van Loo

This paper introduces GRITIC, a method to time genomic gains in tumors, finding that copy number gains often accumulate after genome duplication.

21 citationstop 4%

humanbulk RNA-seq

𝕏 PostBluesky